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喝甘菊茶降低患甲状腺癌的风险(中英译)

最近,一份小型的病例对照研究首次指出,长期喝草药茶(特别是甘菊茶)可能降低患甲状腺癌及其他甲状腺疾病的风险。该研究由雅典预防医学研究所的研究团队完成,结果发表在最新一期的European Journal of Public Health杂志上。

茶是世界上最被广泛饮用的,仅次于水的饮料之一。之前已有研究证实喝茶可能起到降低癌症风险的作用,但却极少有研究深入到内分泌肿瘤的层次。这项最新的研究纳入了113例已通过组织病理学证明患有甲状腺癌的患者,与138名健康对照患者相匹配;同时,该研究还纳入了286例患有良性甲状腺疾病的患者,以揭示喝茶与一般甲状腺疾病之间的联系。

根据饮茶的频率和持续时间——无饮茶习惯、每周至多1次、每周26次、或每天至少1次;以及不足1年、15年以内、1530年、或30年以上,研究团队将参与者进行了分类、统计。结果显示,随着饮茶(甘菊茶)频率的增加,患恶性、良性或其他任何类型甲状腺疾病的风险都显著降低,该结果在校正年龄、性别和BMI参数后,仍具有非常显著的关联性。

相对于那些不饮茶的人,每周喝茶26次的参与者患甲状腺癌的风险要低得多,该结果不受吸烟、饮酒和咖啡等因素的明显影响。研究还发现,随着饮甘菊茶年限的增加,患恶性和良性甲状腺疾病的几率均显著降低,尤其是那些饮茶超过30年的参与者。除了甘菊茶,高山茶和鼠尾草茶对患者也具有保护效应,但没有甘菊茶的效果明显。

作者推测,喝茶降低患良性和恶性疾病的潜在机制可归因于茶含有多酚类,类黄酮和儿茶酚活性成分,源于它们所具有的抗氧化、抗炎和抗肿瘤活性。作者最后也指出,尽管联系显著,仅通过病例对照研究尚不能建立明确的因果关系。因此,还需更多的临床和基础研究来进一步证实该流行病学调查所发现的结果,以及揭示饮茶所蕴含的疾病保护机制。

编注:甘菊茶(Chamomile Tea),又叫洋甘菊茶,多以西式茶的形式出现。甘菊茶饮品迄今已有上千年的历史,具有抗衰老和凝神静气的作用,长期饮用有助于排除体内毒素、消炎、美白润肤,还能适当缓解压力,帮助睡眠,是西方注重健康人群的首选饮品。现在,我们又发现了一项新的功效——长期饮用甘菊茶可降低患甲状腺疾病的风险!

The effect of Greek herbal tea consumption on thyroid cancer: a case-control study

Background: Although in the last decade several studies have addressed the protective role of black and green tea on several diseases, including cancer, there are only few and controversial studies on the effect of tea on benign and malignant thyroid diseases. 

Methods: An age and gender group matched case-control study conducted in Athens, Greece, was designed. 113 Greek patients with histologically confirmed thyroid cancer and 286 patients with benign thyroid diseases along with 138 healthy controls were interviewed with a pre-structured questionnaire in person by trained interviewers. 

Results: An inverse association between chamomile tea consumption and benign/malignant thyroid diseases was found (P < 0.001). The odds of chamomile tea consumption, two to six times a week, after controlling for age, gender and BMI, were 0.30 (95% CI: 0.10–0.89) and 0.26 (95% CI: 0.12–0.5) for developing thyroid cancer and benign thyroid diseases, respectively when compared with not consumption. The duration of consumption was also inversely associated with the diseases. Thirty years of consumption significantly reduced the risk of thyroid cancer and benign thyroid diseases development by almost 80%. Similar, although weaker protective association, was found for sage and mountain tea. Adjustment for smoking, alcohol and coffee consumption did not alter the results. 

Conclusions: Our findings suggest for the first time that drinking herbal teas, especially chamomile, protects from thyroid cancer as well as other benign thyroid diseases.

Reference: http://www.ncbi.nlm.nih.gov/pubmed/25842380?dopt=Abstract

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